Research interests
Biomimetic materials, smart materials, biomaterials, polymer composites, nanostructures, hybrid materials, cellular engineering structures, tissue engineering.
Field of knowledge according to the OECD classifier
Medical technologies, industrial biotechnologies, chemical sciences, materials engineering.
PhD in physics and mathematics, Head of the College of Biomedical Engineering
2021 — present: director of the Center for Biomedical Engineering, NUST MISIS.
2018 — present: associate professor at the NUST MISIS Department of Physical Chemistry.
PhD in physics and mathematics, NUST MISIS.
Main results of scientific work
Biomaterials and implants were developed and tested in clinical cases.
Scopus Hirsch Index — 14.
Number of articles on Scopus — 60.
SPIN RSCI:
ORCID: 0000-0003-3907-5344.
ResearcherID: A-7017-2014.
Scopus AuthorID: 47062114900.
Significant research projects, grants
- Development of a bioresorbable composite material based on polyhydroxyalkanoates for tissue engineering (State Contract No. 14.512.11.0009, March 7, 2013) (Federal Target Program, RUB 9 million, principal investigator).
- Development of a bilayer bioengineering structure based on ultra-high molecular weight polyethylene for reparative surgery of flat and tubular bones using growth factors and cellular technologies (Subsidy Provision Agreement with the Ministry of Education and Science of Russia dated September 19, 2014 No. 14.578.21.0055) (Federal Target Program, RUB 57 million, principal investigator).
- Development of porous polymer bioengineering structures with a bioactive component for tissue engineering using 3D printing technologies (Subsidy Provision Agreement with the Ministry of Education and Science of Russia dated October 21, 2014 No. 14.575.21.0088) (Federal Target Program, RUB 16.2 million, principal investigator).
- Development of principles for the creation of biocompatible polymer nanocomposites with programmable characteristics for endoprosthetics of large joints (Subsidy Provision Agreement with the Ministry of Education and Science of Russia dated November 27, 2014 No. 14.578.21.0083) (Federal Target Program, RUB 15 million, principal investigator).
- Composite materials of a new generation based on thermoplastic polymer matrices filled with quasicrystals (Subsidy Provision Agreement with the Ministry of Education and Science of Russia dated June 5, 2014 No. 14.578.21.0003) (Federal Target Program, RUB 43.5 million, investigator).
- Polymer nanocomposites for combined radio and radiation protection (Subsidy Provision Agreement with the Ministry of Education and Science of Russia dated June 27, 2014 No. 14.575.21.0041) (Federal Target Program, RUB 25 million, investigator).
- Individualized cell-engineered construction for osteoplasty based on a hybrid polymer framework imitating the structural features of bone tissue, impregnated with an antibacterial drug (Subsidy Provision Agreement with the Ministry of Education and Science of Russia dated September 26, 2017 No. 14.578.21.0235) (Federal Target Program, RUB 60 million, investigator).
- Russian Science Foundation: Fundamentals of the formation of cellular structures in ultra-high molecular weight polyethylene (UHMWPE) as matrices for modeling 3D cell culture, 2018 (RUB 6 million).
- Russian Science Foundation: Development of new implantable materials with rhBMP-2 and erythropoietin for reconstructive surgery, 2019 (RUB 6 million).
- Russian Science Foundation: Study of the operando evolution of structural elements in composite and hybrid polymer-matrix materials during the development of the shape memory effect
(21-73-20205).
Significant publications
- Fedor Senatov, Gulbanu Amanbek, Polina Orlova, et al. Biomimetic UHMWPE/HA scaffolds with rhBMP-2 and erythropoietin for reconstructive surgery / Materials Science and Engineering: C, 111 (2020) 110750. [IF=5.880]. Link.
- Bulygina I, Senatov F, Choudhary R, et al, Biomimetic scaffold fabricated with a mammalian trabecular bone template, Polymer Degradation and Stability 172 (2020) 109076. [IF=4.032]. Link.
- Alexander Chubrik, Fedor Senatov, Evgeniy Kolesnikov, et al, Highly porous PEEK and PEEK/HA scaffolds with Escherichia coli-derived recombinant BMP-2 and erythropoietin for enhanced osteogenesis and angiogenesis / Polymer Testing, 2020, 106518. [IF=3.275]. Link.
- А.А. Stepashkin, D.I. Chukov, F.S. Senatov, A.I. Salimon, A.M. Korsunsky, S.D. Kaloshkin,
- 3D-printed PEEK-Carbon Fiber (CF) composites: Structure and thermal properties / Composites Science and Technology, 2018, Volume 164, Pages
319-326. [IF=7.094]. Link. - F.S. Senatov, M.Yu. Zadorozhnyy, K.V. Niaza, V.V. Medvedev, S.D. Kaloshkin, N.Yu Anisimova, M.V. Kiselevskiy, Kai-Chiang Yang. Shape memory effect in 3D-printed scaffolds for self-fitting implants / European Polymer Journal 93C (2017) pp.
222-231 [IF=3.862] - A.V. Maksimkin, F.S. Senatov, N.Yu. Anisimova, M.V. Kiselevskiy, D.Yu. Zalepugin, I.V. Chernyshova, N.A. Tilkunova, S.D. Kaloshkin. Multilayer porous UHMWPE scaffolds for bone defects replacement / Materials Science and Engineering: C 73 (2017)
366–372 [IF=5.880]. Link. - F.S. Senatov, K.V. Niaza, A.A. Stepashkin, S.D. Kaloshkin. Low-cycle fatigue behavior of 3d-printed PLA-based porous scaffolds / Composites Part B 97 (2016)
193–200 [IF=7.635]. Link. - Senatova S.I., Senatov F.S., Kuznetsov D.V., Stepashkin A.A., Issi J.P. Effect of UV-radiation on structure and properties of PP nanocomposites / Journal of Alloys and Compounds DOI: 10.1016/j.jallcom.2016.11.170 [IF=4.650].
- F.S. Senatov, K.V. Niaza, M.Yu. Zadorozhnyy, A.V. Maksimkin, S.D. Kaloshkin, Y.Z. Estrin. Mechanical properties and shape memory effect of 3D-printed PLA-based porous scaffolds / Journal of the Mechanical Behavior of Biomedical Materials, V. 57, 2016, P.139—148 [IF=3.372]. Link.
- F.S. Senatov, A.N. Kopylov, N.Yu. Anisimova, M.V. Kiselevsky, A.V. Maksimkin. UHMWPE-based nanocomposite as a material for damaged cartilage replacement / Materials Science and Engineering C 48 (2015)
566–571 [IF=5.880]. Link.
Significant patents
- Russian patent for invention No. 2637841 dated December 07, 2017: Bioactive polymer filament for layered 3D printing.
- Russian patent for invention No. 2603477 dated November 2, 2016: Method for sterilizing ultrahigh molecular polyethylene intended for medical uses (options).
- Russian patent for invention No. 2625454 dated July 14, 2017: Polymer nanocomposite material for tribotechnical uses with an oriented structure.
- Russian patent for invention No. 2631889: Insert of the acetabular component of the hip joint endoprosthesis made of polymer nanocomposite material.
- Russian patent for invention No. 2665175 dated August 28, 2018: Bioactive polymer porous framework.
- Russian patent for invention No. 2632785 dated October 9, 2018: Hybrid porous construction for the replacement of osteochondral defects.
- Russian patent for invention No. 2634860 dated November 7, 2017: Bioengineering scaffold with an antibacterial coating to replace bone-cartilage defects.
- Russian patent for invention No. 2708528 dated December 9, 2019: Hybrid metal-polymer construction for medical uses.
- Russian patent for invention No. 2743108: Hybrid plate for cranioplasty.
- Eurasian patent No. 036376 dated November 2, 2020: Shape memory polymer composite for 3D printing of medical items.
Scientific supervision and teaching
11 bachelors, 9 masters, 1 postgraduate.
Teaching
- “Polymer materials for medical applications” (master’s degree iPhD “Biomaterials science”, NUST MISIS).
- Physical chemistry (bachelor’s degree, NUST MISIS).
- Guest lecturer at the Technische Universitat Dortmund (Germany).
- Guest lecturer at the University of Lorraine (France).
Scientific and social activities
Guest editor of special issue “Applications of biopolymer Scaffolds” in Polymers (Q1).
Guest editor of special issue “Polymer composites and bioactive materials for tissue engineering” in Polymers (Q1).
Working groups on science and education.
