Scientists from NUST MISIS have found out how to improve the alloy for maxillofacial implants

Based on the experiments, scientists from NUST MISIS have identified a methodology that improves the balance of strength and ductility of the biodegradable magnesium alloy used in biomedicine, particularly for maxillofacial implants. The peculiarity of the material lies in the fact that after the operation, it gradually dissolves in the human body. Fixing elements (screws, pins, plates, etc.) made of magnesium alloy are completely replaced by newly formed tissue, eliminating the need for a second operation to remove temporary elements from the human body. In recent years, researchers have been interested in the magnesium, zinc, and gallium alloy (Mg-Zn-Ga). The addition of zinc and gallium improves the mechanical and corrosion properties, allowing the integrity of the implant to be maintained for a certain period necessary for the healing process. Zinc contributes to the strengthening of the material, while gallium enhances its ductility, imparts antimicrobial properties, and increases bone tissue density. Due to its characteristics, this alloy is much closer to human bone tissue than titanium.

Researchers at NUST MISIS have developed a platform for detecting diseases at early stages

Scientists from the MISIS University, in collaboration with colleagues from Skoltech and the National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov, have developed a platform for detecting clinical biomarkers of diseases in human biological fluids in real-time. It could serve as the first step towards creating a portable lab-on-a-chip for early detection of cancer, neurodegenerative, and cardiovascular diseases, as well as for monitoring treatment.

Manipulating the Earth’s crust under extreme stress conditions can lead to man-made earthquakes, NUST MISIS scientist claims

Earthquakes can be caused not only by natural factors; some strong ground movements in industrial zones have a mixed nature, such as natural-technogenic or technogenic-tectonic. The trigger for these can be engineering interventions in the subsurface. A scientist from NUST MISIS highlighted the need to study geodynamic effects related to the extreme stress state of the Earth’s subsurface in areas where mining activities are conducted.

Russian scientists have refuted the sensational conclusion made by researchers about the possibility of breaking quantum algorithms

A team of scientists from the MISIS University, RQC, and Sber conducted a thorough analysis of the calculations used by researchers from Zhengzhou, Beijing, and Hangzhou institutions to simulate the breaking of a cryptosystem using a 350+ qubit quantum computer and questioned their sensational conclusion about a revolution in cryptography. Russian scientists believe that the colleagues’ algorithm is not functional due to some “pitfalls” in the classical part and the complexity of the quantum part’s implementation.

The world’s first operation using bioprinting on a patient was performed with the help of a bioprinter created at NUST MISIS

The Main Military Clinical Hospital named after Academician N.N. Burdenko conducted the world’s first operation using a bioprinter consisting of a robotic arm, a bioprinting system, and computer vision. The device was developed by scientists at NUST MISIS and the pioneers of Russian bioprinting, the company 3D Bioprinting Solutions. The trajectory of the in situ biopolymer delivery, directly into the wound, was programmed on-site by a university specialist after scanning the site of the injury. The surgeon harvested the patient’s cells from the bone marrow and then added them to bio-ink for printing. The robot conducted the scanning and bioprinting without human involvement. According to the medical professionals at the center, this equipment opens up entirely new possibilities for treating complex extensive soft tissue defects.

A new approach to studying neurons will help understand the mechanisms of Alzheimer’s disease development

The research group of NUST MISIS, along with colleagues from the Russian Academy of Sciences’ Institute of Molecular Biology, demonstrated the efficiency of a fundamentally new method for analyzing neuronal cells. Using the only scanning ion-conducting microscope in Russia with a confocal module, scientists have revealed that Alzheimer’s disease causes neuronal cells to become mechanically stiffer because amyloid aggregates formation on their surface.. Novel therapeutic agents for Alzheimer’s disease treatment are currently being examined using this innovative scientific equipment.

NUST MISIS scientists create new materials for the space industry and nuclear energy

Researchers at MISIS University have introduced new materials called hafnium-zirconium carbonitrides. These materials can be used as components of matrix nuclear fuel or thermal protection for spacecraft. The chief advantage of these materials over their carbide predecessors lies in their increased resistance to high-temperature oxidation. The service life of the product and the upper limit of working temperatures hinge on this property.

Scientists from NUST MISIS have proposed a new approach to modify alloy surfaces for medical purposes

Researchers from NUST MISIS have proposed a new two-stage method for modifying alloys, which are promising for manufacturing orthopedic implants that require special mechanical and functional properties. By using atomic layer deposition on the surface of a superelastic Ti-Zr-Nb (titanium-zirconium-niobium) alloy, they were able to obtain an oxide film (TiO₂) that allows for controlling the chemical state of the material. Subsequently, silver nanoparticles were applied to the alloy, significantly increasing the antibacterial activity of the material.

Steel that saves lives

Scientists from NUST MISIS, in collaboration with Severstal, have developed a new Russian fire-resistant grade of steel, C390P, for industrial and civil facilities such as trade and business centers, warehouses, transport hubs, and multi-story garages. Structural metal constructions made from this steel can withstand a fire temperature of 600°C for about 30 minutes without losing their load-bearing capacity. This helps slow down the destruction of buildings during fires, providing additional time for people to evacuate. Fire-resistant products made from C390P steel are already being produced at the Severstal Steel Solutions plant. The project was implemented with the support of the Russian government as part of the program to develop high-tech domestic production. The development received a gold medal at the Metal-Expo 2023 exhibition.

NUST MISIS scientists patent a biodegradable alloy for bone implants

Researchers at the MISIS University have patented a shape memory alloy for biodegradable bone implants based on an iron-manganese-silicon (Fe-Mn-Si) system. It possesses high biomechanical compatibility with bone tissue and the required rate of dissolution, making it a promising material for use in traumatology, orthopedics and maxillofacial surgery.